Project Manager (Construction) – Pharma Manufacturing Projects

A leader in Life Sciences Manufacturing Technology solutions, AMTSOL partners with global pharmaceutical and biotechnology organizations to deliver Automation, MES, CSV, CQV, and Digital Transformation solutions across Singapore, Europe, and the USA.

Project Manager (Construction) – Pharma Manufacturing Projects

Location: Morrisville, NC

Job Description (JD): Construction Manager – GMP Facility Set-Up (Life Sciences / Pharma)

Position Title: Construction Manager – GMP Facility Set-Up (Life Sciences / Pharma)
Function: Project / Construction Management (Capital Projects)
Industry: Pharmaceutical / Biotech / Life Sciences (GMP Regulated Manufacturing)
Employment Type: Full-time / Contract (as applicable)
Reporting To: Project Director / Head of Engineering / Site Project Lead

Role Summary

We are seeking a hands-on Construction Manager with hard-core, onsite experience delivering GMP greenfield/brownfield facility set-ups, including construction, fit-out, and readiness for regulated manufacturing environments. The role requires strong coordination across contractors, engineering, CQV, EHS, and Quality to drive execution through mechanical completion and support commissioning & qualification toward GMP operation.

Key Responsibilities

1) Construction Delivery (GMP Projects)

• Lead site construction execution for GMP manufacturing / DS/DP facilities including fit-out, cleanroom build, and controlled area readiness. 
• Manage daily construction activities ensuring scope, schedule, and cost targets are met. Oversee construction progress through mechanical completion and readiness milestones. 
• Coordinate with multiple contractors and subcontractors for civil, structural, architectural, MEP, clean utilities, and process support works.

2) Contractor & Stakeholder Management

• Perform daily coordination with contractors, resolve site issues, and drive corrective actions to maintain momentum. 
• Partner closely with Engineering, Automation, CQV, and operations teams to ensure construction aligns to commissioning sequence and GMP start-up needs. 
• Maintain strong interfaces with Quality Assurance for GMP alignment, inspections, audit readiness, and compliance expectations.

3) Project Management & Controls

• Support/lead preparation of key project documentation such as:
  • Project/Business Requirements, WBS, CBS, Scope Statements, execution plans. 
  • Track progress, manage changes, coordinate punch list closure, and ensure structured handover to CQV/Operations.
• Monitor contractor productivity, review schedules, align look-ahead plans, and report weekly status to leadership.

4) Safety, Quality & Compliance (EHS/GMP)

• Enforce site safety standards, permit-to-work systems, and contractor EHS compliance.
• Ensure construction documentation (drawings, redlines, turnover packs, IQ support documents, vendor dossiers) is complete and compliant for GMP handover.
• Ensure construction works meet GMP expectations for finishes, material flow, contamination control, and segregation principles.

5) Commissioning, Qualification & Handover Support

• Work collaboratively with CQV teams to support construction completion, system boundaries, turnover, and readiness for commissioning activities.